PicoLO Premium: Complete Buyer's Guide
analytics Quick Specifications
Wavelengths
PicoLO Premium is Laseroptek's second-generation picosecond Nd:YAG platform built around 1064nm and frequency-doubled 532nm output. The supplied September 2026 profile identifies only these two native treatment wavelengths.
There is no native 755, 785, 730 or 694nm source. Buyers whose case mix depends heavily on specialty wavelengths should confirm that the two-wavelength architecture fits their patient population.
Pulse Duration
The FDA-filed platform delivers 450ps at 1064nm and 380ps at 532nm, with ±20% noted in the executive summary. Current global materials may state 450/350ps, so buyers should verify the exact quoted configuration and documentation.
Commercial testing is described as showing high pulse and energy stability, supporting predictable LIOB and treatment consistency.
Energy & Fluence
FDA-filed Tattoo Mode values are 500mJ at 1064nm and 350mJ at 532nm. The supplied profile characterizes these as moderate versus some high-energy competitors. Some international materials reportedly state 600/400mJ, so buyers should lock down serial-specific specifications.
Spot Sizes
The FDA record lists 10mm at 1064nm, 7mm at 532nm, a 20mm collimator and 2–7mm zoom. Dia FX fractional patterns are configuration-specific.
Fractional Technology
Dia FX: DOE fractional handpieces provide three selectable tissue-depth settings. The supplied profile describes multi-depth fractional delivery as a defining advantage.
Dia FX 1064 and 1064 S handpieces are described as offering three selectable tissue-depth settings. The system supports fractional treatment without disposable fractional cartridges; reusable optical handpieces may reduce per-treatment consumable expense.
Treatment Capabilities
The supplied executive summary describes FDA-cleared indications covering multicolor tattoo removal, benign pigmented lesions, acne scars and wrinkles. It also describes zoom, 10mm, 20mm collimated and multiple fractional delivery formats for focal and large-area work.
FDA-Cleared Indications
- Multicolor tattoo removal — original PicoLO clearance dated January 4, 2019.
- Benign pigmented lesions — added in the April 7, 2021 clearance.
- 1064nm treatment of acne scars — added in the April 7, 2021 clearance.
- Wrinkles — added in the April 7, 2021 clearance.
Key Strengths
- Unusually broad FDA-cleared clinical scope including tattoos, benign pigment, acne scars and wrinkles.
- Multi-depth DOE fractional delivery with three selectable tissue-depth settings.
- High pulse and energy stability supporting treatment consistency.
- Diverse treatment geometry including zoom, 10mm, 20mm collimated and fractional formats.
- Reusable optical handpieces; no disposable fractional cartridges are described in the supplied profile.
Buyer Considerations
PicoLO Premium has only two native treatment wavelengths and moderate FDA-filed pulse energy compared with some high-energy competitors.
Published specifications differ across sources: some international materials report 600/400mJ and 350ps at 532nm, while FDA-filed values in the supplied profile are 500/350mJ and 380ps. Buyers should verify the exact quoted configuration.
The FDA record specifies 220–230VAC, which may require dedicated electrical work. The value proposition is also handpiece-heavy, so a complete and undamaged Dia FX, zoom and collimator package matters.
Warranty & Service
Warranty terms are not publicly standardized in the supplied profile. Confirm duration and exclusions for source, articulated arm, optics, handpieces, parts, labor and travel. The manufacturer/U.S. channel is identified as Laseroptek Co., Ltd. with Laseroptek America; confirm the legal seller and servicing entity.
Approximate Pricing
Estimated New Planning Range
Manufacturer quotation required for the exact U.S. package, configuration and promotions.
Pre-Owned
The supplied profile does not provide a standardized used-market price.
Who Might Consider This Platform?
PicoLO Premium may suit a dermatology, plastic-surgery or advanced medical-aesthetic practice whose revenue plan includes pigment, acne-scar and wrinkle programs in addition to tattoo removal.
It is particularly compelling for clinicians who value controlled LIOB, reusable fractional optics and selectable treatment depth more than specialty wavelengths or category-leading pulse energy.
Pico Laser Interactive Spotlight Table
Click any column header to sort from highest to lowest and lowest to highest
| PicoTech | 5 Standard: 1064, 532, 755, 585, 650nm | 2 Standard – Honeycomb 120px & 1064 DOE 49px | 350ps | 350ps | 800mj | 25.46 J/cm2 | 2 Years | $60,000 |
| PicoSure Pro | 1 Standard: 755nm (532, 1064nm optional) | 1 Standard Platinum Focus™ Lens Array | 900ps (500ps@755) | 450ps | 300mj | 9.55 J/cm2 | 1 Year | $200,000 |
| PicoWay | 2 Standard: 1064, 532nm (730, 785nm optional) | 0 Standard – Resolve Fractional optional | 343ps | 294ps | 400mj | 12.73 J/cm2 | 1 Year | $250,000 |
| Discovery Pico | 2 Standard: 1064, 532nm (694nm ruby on Plus) | 0 Standard – Optional Microbeam HC/DF | 450ps | 370ps | 800mj | 25.46 J/cm2 | 1 Year | $160,000 |
| PicoPlus | 2 Standard: 1064, 532nm (595, 660nm optional) | 0 Standard – Optional Dual Focused Dots | 450ps | 450ps | 800mj | 25.46 J/cm2 | 1 Year | $160,000 |
| PicoCare Majesty | 2 Standard: 1064, 532nm (595, 660nm optional) | 0 Standard – Optional MLA/DOE | 250ps | 180ps | 500mj | 15.92 J/cm2 | 1 Year | $125,000 |
| PicoLazer | 2 Standard: 1064, 532nm | 1 Standard – Fractional Handpiece | 450ps | 450ps | 500mj | 15.92 J/cm2 | 1 Year | $95,995 |
| PicoLO Premium | 2 Standard: 1064, 532nm | 1 Standard – Dia FX fractional | 450ps | 380ps | 500mj | 15.92 J/cm2 | 1 Year | $150,000 |
| PicoStar | 2 Standard: 1064, 532nm | 0 Standard – Optional MicroSpot PICO | 300ps | 300ps | 800mj | 25.46 J/cm2 | 1 Year | $180,000 |
| StarWalker PICO Pro | 2 Standard: 1064, 532nm (585, 650nm optional) | 1 Standard – FracTAT® & FracRevive | 300ps | 300ps | 800mj | 25.46 J/cm2 | 1 Year | $180,000 |
| PicoClear | 4 Standard: 1064, 532, 585, 650nm | 1 Standard – PicoLift 7×7 fractional | 350ps | 300ps | 450mj | 14.32 J/cm2 | 1 Year | $120,000 |
| PICOHI 300 | 2 Standard: 1064, 532nm | 0 Standard – Optional VMLA, ZMLA, DOE | 300ps | 275ps | 500mj | 15.92 J/cm2 | 1 Year | $95,000 |
| PicoFusion HS-298 | 2 Standard: 1064, 532nm | 0 Standard – Optional MLA/DOE | 350ps | 300ps | 500mj | 15.92 J/cm2 | 2 Years | $129,000 |
| Picofy | 2 Standard: 1064, 532nm | 0 Standard – Optional Array MLA 110 & Peak MLA 60 | 300ps | 300ps | 500mj | 15.92 J/cm2 | 1 Year | $160,000 |
| enlighten III | 3 Standard: 1064, 532, 670nm | 0 Standard – Optional MLA Handpiece | 750ps | 750ps | 600mj | 19.10 J/cm2 | 1 Year | $180,000 |
| PiQo4 | 4 Standard: 1064, 532, 585, 650nm | 0 Standard | 500ps | 500ps | 650mj | 20.69 J/cm2 | 1 Year | $180,000 |